Tag: CC21

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

Diagnosis and Treatment of VTE in the COVID-19 era

Ed – this post supports a webinar Dan gave with Thrombosis UK. We hope to link to that content when it’s ready. First of all, thanks to Thrombosis UK for inviting me to speak at

COVID-19: Journal Club #2 – The Webinar

Welcome to our second webinar on recent research about COVID-19, hosted by the University of Manchester, Manchester Royal Infirmary and Royal College of Emergency Medicine in collaboration with St Emlyn’s. The live event took place

JC: Conservative management of pneumothoraces.

When I trained here in Virchester we had a fairly aggressive approach to the management of pneumothoraces. All trauma pneumothoraces got chest drains, a chest drain meant an open one, the size was as big

JC: D-K-hoorAy! New Paeds DKA guidelines

On Monday, the British Society for Paediatric Endocrinology and Diabetes published interim guidelines on the management of diabetic ketoacidosis (DKA) in our younger patients (under the age of 18). NICE are planning to fully review

2019 Novel Coronavirus (Wuhan) at St Emlyn’s

Thursday afternoon, I brazenly told my director that the coronavirus needn’t warrant immediate concern.  I didn’t want to add to the typical hysteria that leads to people purchasing too many medical supplies that then results

The VITAMINS trial

JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis. St Emlyn's

You may remember the controversy about Paul Marik’s suggestions that a combination of Vitamin C, steroids and Thiamine (sometimes known as HAT​1​) is a cure all for sepsis. There were some rather dramatic claims that

JC: The PEPTIC study PPI vs H2RBs on the ICU. St Emlyn's

The PEPTIC study is a randomised controlled trial of a Proton Pump Inhibitor (PPI) vs. Histamine-2 Receptor Blockers for ulcer prophylaxis on the ICU. Think Omeprazole vs. Ranitidine as your choice of prophylaxis. Although there

#CCR20

JC: Critical care reviews meeting day 1 #CCR20. St Emlyn's

In addition to the breaking trials at the #CCR meetings a number of other important trials were presented that you should seek out and review. We’ve not done full critical appraisals on these trials, that’s

JC: The 65 trial. Targeting MAP in sepsis. St Emlyn's at #CCR20

Editors note: This blog is based on the presentation of the 65 trial at the Critical Care Reviews conference in Belfast. We will add more data, and be able to add a more detailed critical


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