Tag: CC21

The VITAMINS trial

JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis. St Emlyn's

You may remember the controversy about Paul Marik’s suggestions that a combination of Vitamin C, steroids and Thiamine (sometimes known as HAT​1​) is a cure all for sepsis. There were some rather dramatic claims that

JC: The PEPTIC study PPI vs H2RBs on the ICU. St Emlyn's

The PEPTIC study is a randomised controlled trial of a Proton Pump Inhibitor (PPI) vs. Histamine-2 Receptor Blockers for ulcer prophylaxis on the ICU. Think Omeprazole vs. Ranitidine as your choice of prophylaxis. Although there

#CCR20

JC: Critical care reviews meeting day 1 #CCR20. St Emlyn's

In addition to the breaking trials at the #CCR meetings a number of other important trials were presented that you should seek out and review. We’ve not done full critical appraisals on these trials, that’s

JC: The 65 trial. Targeting MAP in sepsis. St Emlyn's at #CCR20

Editors note: This blog is based on the presentation of the 65 trial at the Critical Care Reviews conference in Belfast. We will add more data, and be able to add a more detailed critical

JC: IN Fentanyl vs Ketamine for analgesia in PED. St Emlyn’s

Last year we reviewed a pilot RCT comparing IN Fentanyl vs IN Ketamine in kids​1,2​. We concluded that they were probably similar in analgesic effect but that Ketamine had a higher adverse event rate. Here

reboa stemlyns

REBOA with Zaf Qasim. St Emlyn’s

This week we are publishing a podcast with Zaf Qasim on REBOA. Zaf is a St Emlyn’s team member and Virchester alumnus although he now works over in the US having completed his critical care

European Resuscitation Council meeting: Slovenia 2019. St Emlyn’s

This month I was lucky enough to be invited to speak in Slovenia at the European Resus Council meeting. It was a super place to visit and a wonderful conference. The theme of the conference

JC: Lower GI bleeding guidance. St Emlyn’s

The management of the patient with apparent lower GI (gastro-intestinal) bleeding is, in my experience at least, somewhat variable. Unlike upper GI bleeding where the standards and expectations are reasonably well known​1,2​, the lower GI

JC: Enter Sandman – Which Agent as Second Line in Paediatric Status Epilepticus?

Appraisal and reflections on the recently published ConSEPT and EcLiPSE trials – what do they mean for the treatment of paediatric status epilepticus?

JC: Pulmonary embolism, ambulatory care and the goddess of the hunt

This post covers a talk I was asked to give at the recent RCEM CPD conference in Belfast. A great event, and well hosted in spite of the LOC chair becoming indisposed by imminent fatherhood.

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