Musings form the evidence based journal club at St Emlyns
Category: Journal Club
JC: Re-evaluating risk factors for Cauda Equina. St Emlyn’s
The diagnosis of cauda equina in the emergency department is complex and has the potential for significant patient harm if we get it wrong. Linda Dykes put together an excellent infographic on this back in …
JC: The REST trial. St Emlyn’s
Some years ago I remember speaking to a rather well known intensivist who was advocating for the extracorporeal removal of CO2 in ICU patients. His logic was that in patients with hypoxic lung failure we …
JC: CTCA for cardiac chest pain in the ED. St Emlyn’s
Computed Coronary Angiography (CTCA) has been advocated as a useful adjunct in the investigation of acute coronary syndromes (ACS) in the ED. Although we’ve made huge progress in the diagnosis of ACS through the use …
Top 10 Trauma Papers for Trauma UK conference. 2020-2021. St Emyln’s
It’s that time of year again when the Trauma Care UK conference comes around and I get to talk about 10 interesting trauma papers from the last 12 months or so. This is a regular …
JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial. St Emlyn’s
I remember back at the beginning of the pandemic when we were seeing lots of patients arriving in the ED in extremis. The now familiar picture of the deeply hypoxic patient with terrible chest X-rays …
JC: Thromboprophylaxis for the non ICU hospitalised COVID-19 patient. St Emlyn’s
Back in March we reported on a pre-print trial of thromboprophylaxis of ICU patients. The results suggested that there was no benefit for therapeutic dose anticoagulation in COVID19 as a prophylactic strategy for critically ill patients with COVID19. This …
JC: The TTM2 trial. Normothermia or hypothermia post cardiac arrest.
A quick update on an TTM2 trial published in the NEJM last month. As part of the chain of survival it’s important to optimise the post resuscitation phase, primarily to preserve neurological function as this …
REGN monoclonal antibodies work in selected hospitalised COVID-19 patients. St Emlyn’s
We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. In the last month the RECOVERY trial has …
May 2021 Podcast round up. St Emlyn’s
Our regular round up of the blog highlights in podcast form as hosted by Ian and Simon.
JC: Aspirin is not effective for hospitalised COVID19 patients. St Emlyn’s
We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. This week the RECOVERY trial has released the …
