All posts by Simon Carley

Professor Simon Carley MB ChB, PGDip, DipIMC (RCS Ed), FRCS (Ed)(1998), FHEA, FAcadMed, FRCEM, MPhil, MD, PhD is Creator, Webmaster, owner and Editor in Chief of the St Emlyn’s blog and podcast. He is Professor of Emergency Medicine at Manchester Metropolitan University and a Consultant in adult and paediatric Emergency Medicine at Manchester Foundation Trust. He is co-founder of BestBets, St.Emlyns and the MSc in emergency medicine at Manchester Metropolitan University. He is an Education Associate with the General Medical Council and is an Associate Editor for the Emergency Medicine Journal. His research interests include diagnostics, MedEd, Major incidents & Evidence based Emergency Medicine. He is verified on twitter as @EMManchester

CODA

CODA ZERO update: Gender and Ethics

This week I should be on my way to Australia for the CODA Change conference. For obvious reasons I am not going and am sat at home in Manchester enjoying the last remnants of the

JC: TXA in severe head injury. St Emlyn’s

Our post on the CRASH-3 trial, an RCT examining the use of TXA in head injury, was arguably our most controversial of 2019 (1). Our view was that the evidence was not entirely definitive, but

JC: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock. The ACTS Randomized Clinical Trial St Emlyn’s

Back in 2017 the sepsis world had a rather strong reaction to a paper published by Paul Marik that suggested that a combination of steroid, vitamin C and Thiamine could cure sepsis. The data, published

Look at what they make you give

Ed – We received this post just as the extent of the Coronavirus pandemic was becoming clear and thought it best to delay publishing until life in our Emergency Departments was slightly more “normal”. The

JC: Does post exposure prophylaxis (with HCQ) work in Covid-19?

The utility of hydroxychloroquine in the management of Covid-19 often seems to be more of a political than a medical debate. Many politicians, journalists, hacks, and a whole range of social media experts have an

CODA ZERO is here. St Emlyn’s

This week marks the return of CODA, or rather the start of the CODA project that developed from the genre changing SMACC conferences. I was lucky enough to be involved in setting up the first

Covid-19 in Italy with Roberto Cosentini part 2. St Emlyn’s

Ed – Back at the beginning of the pandemic we had a fantastic contribution from our friend and colleague Roberto Cosentini on the Bergamo experience of dealing with this terrible disease. It turned out to

Top 10 trauma papers 2019-2020 for Liverpool Trauma Seminars. St Emlyn’s

This week I am presenting (virtually) at the Liverpool Trauma Seminar. This is a new initiative that aims to provide a multispeciality, multidisciplinary trauma conference in the North West of England. It’s run out of

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

COVID Journal Club #8 – The Webinar. Thursday 18th 11am BST

We took a well earned break last week from the weekly Covid19 webinar and journal club, but we are back on Thursday with 5​1–5​+1 papers to keep us all thinking about how we use science


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