Salim Rezaie joins the 28 April 2020 COVID-19 journal club, with the recording and paper list collected here. The discussion centres on thrombosis, alongside early reports on awake proning, antibody testing, hospital outcomes and falling acute coronary syndrome admissions.
COVID-19: Journal Club #3 – The Webinar Read More
An April 2020 review of ten COVID-19 papers, covering lung injury, service capacity, biomarkers, antibody testing and population surveillance. It also examines lung ultrasound, hydroxychloroquine and protection in refugee camps, separating promising ideas from evidence that was still preliminary.
COVID-19 Journal Club: The Director’s Cut #2 Read More
Notes from day two of Critical Care Reviews 2020, covering ROSE, CITRIS-ALI and BIRDS, alongside editorial perspectives and the John Hinds Memorial Lecture. These conference highlights signpost research and discussion rather than providing full critical appraisals of every paper.
JC: Critical Care Reviews day 2. #CCR20. St Emlyn's Read More
Did adding vitamin C and thiamine to hydrocortisone improve outcomes in septic shock? This 2020 VITAMINS appraisal examines a randomised comparison that found no improvement in its primary vasopressor-free-time outcome, while discussing the contrast with earlier observational claims and remaining questions about timing and patient selection.
This preview of the September 2018 World Sepsis Conference considers what a free online meeting can offer. Simon Carley reflects on access, diversity, patient voices and the environmental costs of travel, asking how conferences might share learning more widely while retaining the value of meeting in person.
Fluids are drugs, with potential benefits and harms. Simon Carley examines a 2018 narrative review of intravenous fluids in critically ill adults, covering fluid choice, shock phases and evolving physiology. He also asks how to read expert reviews critically and remain open to evidence that challenges established practice.
JC: Intravenous fluid therapy in critically ill adults (review). St Emlyn’s Read More
More oxygen is not necessarily better. This 2018 journal club examines a systematic review comparing liberal and conservative oxygen strategies in acutely ill adults. Simon Carley considers mortality findings, the size of the absolute effect and why even a meta-analysis needs careful critical appraisal.
JC: Oxygen in the Acutely Unwell Patient. St Emlyn’s Read More
SALT-ED compared balanced crystalloids with saline in adults admitted from the emergency department to non-critical-care beds. This 2018 appraisal distinguishes the neutral primary outcome from the signal in kidney outcomes, examining pragmatic trial design, follow-up and the limits of applying one centre’s findings more widely.
JC: So long Salt and Saline? St Emlyn’s Read More
