Understanding COVID-19 testing with Rick Body. St Emlyn’s

This week Simon and Rick got together to talk through the latest technologies, uses and performance of COVID-19 testing. We think it’s a really useful listen to understand the strengths and weaknesses of the various tests and thoughts on where we go next.

We cover a lot of ground, and if you want to know more you can follow the links below.


The FALCON/CONDOR studies led by Rick are the main research studies for assessing COVID-19 tests in the UK.

On clinicaltrials.gov – Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 (FALCON-C19) (FALCON-C19) https://clinicaltrials.gov/ct2/show/NCT04408170

PCR Tests

These are polymerase chain reaction tests. You may remember them from med/clinical school. The method amplifies small fragments of DNA in order to make them detectable. You can reminder yourself of the details here https://en.wikipedia.org/wiki/Polymerase_chain_reaction

LAMP testing

LAMP stands for Loop-mediated Isothermal Amplification is a single tube technique that is easier than PCR and potentially quicker. https://en.wikipedia.org/wiki/Loop-mediated_isothermal_amplification

DNA Nudge

This is commercial product that uses a rapid PCR technique. We talk about this one as it is being used in Virchester https://www.dnanudge.com/en/COVID-Nudge

Lateral flow tests

These are now used for staff testing in the NHS https://en.wikipedia.org/wiki/Lateral_flow_test



Cite this article as: Simon Carley, "Understanding COVID-19 testing with Rick Body. St Emlyn’s," in St.Emlyn's, December 1, 2020, https://www.stemlynsblog.org/understanding-covid-19-testing-with-rick-body-st-emlyns/.

Posted by Simon Carley

Simon Carley MB ChB, PGDip, DipIMC (RCS Ed), FRCS (Ed)(1998), FHEA, FAcadMed, FRCEM, MPhil, MD, PhD is Creator, Webmaster, owner and Editor in Chief of the St Emlyn’s blog and podcast. He is visiting Professor at Manchester Metropolitan University and a Consultant in adult and paediatric Emergency Medicine at Manchester Foundation Trust. He is co-founder of BestBets, St.Emlyns and the MSc in emergency medicine at Manchester Metropolitan University. He is an Education Associate with the General Medical Council and is an Associate Editor for the Emergency Medicine Journal. His research interests include diagnostics, MedEd, Major incidents & Evidence based Emergency Medicine. He is verified on twitter as @EMManchester

Thanks so much for following. Viva la #FOAMed