Tag: EBM

Bayes belief and bias

Bayes and Belief: How pre-review belief influences critical appraisal. St Emlyn’s

I’ve been reflecting on why there is disagreement about how influential new evidence is to clinical practice in the last year or so. COVID-19 has shown that the thresholds for what we believe and when

January 2021 Podcast

January 2021 round up podcast: St Emlyn’s

Our regular round up of the best of the blog and podcast from January 2021 with Iain and Simon. The links to the articles are below together with a link to our podcast. Please don’t

The ‘Roid’ to Recovery? REMAP-CAP @ St Emlyn’s

This week JAMA published three important trials on the use of steroids in patients with severe COVID-19, with an additional cherry on top; a subsequent inclusive meta-analysis (totalling 7 RCTs and 1703 patients) from the

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s

We’ve talked about the RECOVERY trial on the blog and podcast before. This is a UK based platform trial (more on this later) looking at patients admitted to hospital with Covid-19. It’s an open label

Covid-19 journal club

Covid-19 Journal Club: The Director’s Cut #4

We have searched every COVID-19 publication, and summarised the literature of everything published in the last fortnight. We have highlighted those papers that will be of interest to EM clinicians on the front line. This

COVID-19 The Director’s Cut #3

Here we have specially selected, and summarised the literature for COVID-19 in the last week. We have highlighted those papers that will be of interest to EM clinicians on the front line. This is part

COVID-19: Journal Club #3 – The Webinar

Welcome to our third webinar and journal club reviewing recent research and featuring COVID-19 updates, hosted by the University of Manchester, Manchester Royal Infirmary and Royal College of Emergency Medicine in collaboration with St Emlyn’s.

COVID-19 Journal Club: The Director’s Cut #2

References Gattinoni, L., Chiumello, D., Caironi, P., Busana, M., Romitti, F., Brazzi, L. and Camporota, L., 2020. COVID-19 pneumonia: different respiratory treatments for different phenotypes?. Intensive Care Medicine, p.1. Giannakeas, V., Bhatia, D., Warkentin, M.T., Bogoch,

COVID-19 and Blood Clots: Diagnosis, D-dimers and Dilemmas

In a future post I’ll discuss the latest NICE guidance​1​ on the diagnosis and management of venous thromboembolism. When writing that though I knew that for many of you COVID-19 currently consumes you and all