Tag: CC3

Top 10 trauma papers 2019-2020 for Liverpool Trauma Seminars. St Emlyn’s

This week I am presenting (virtually) at the Liverpool Trauma Seminar. This is a new initiative that aims to provide a multispeciality, multidisciplinary trauma conference in the North West of England. It’s run out of

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

JC: Halt! It’s not time for TXA! Or is it? HALT-IT results at St Emlyn’s

If you’re any kind of emergency care aficionado, you probably worship at the altar of tranexamic acid (TXA). With data showing more favourable outcomes from its use in traumatic bleeding​(1)​, post-partum haemorrhage​(2)​, maybe traumatic brain

The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s

We’ve talked about the RECOVERY trial on the blog and podcast before. This is a UK based platform trial (more on this later) looking at patients admitted to hospital with Covid-19. It’s an open label

JC: AVP in Haemorrhagic Shock. St Emlyn’s

Blood product transfusion can be lifesaving for patients who have suffered major trauma, but the associated side-effects and risks, mean that most people would agree that less is more. This paper by Sim et al

JC: D-K-hoorAy! New Paeds DKA guidelines

On Monday, the British Society for Paediatric Endocrinology and Diabetes published interim guidelines on the management of diabetic ketoacidosis (DKA) in our younger patients (under the age of 18). NICE are planning to fully review

The VITAMINS trial

JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis. St Emlyn's

You may remember the controversy about Paul Marik’s suggestions that a combination of Vitamin C, steroids and Thiamine (sometimes known as HAT​1​) is a cure all for sepsis. There were some rather dramatic claims that

JC: The PEPTIC study PPI vs H2RBs on the ICU. St Emlyn's

The PEPTIC study is a randomised controlled trial of a Proton Pump Inhibitor (PPI) vs. Histamine-2 Receptor Blockers for ulcer prophylaxis on the ICU. Think Omeprazole vs. Ranitidine as your choice of prophylaxis. Although there

JC: The 65 trial. Targeting MAP in sepsis. St Emlyn's at #CCR20

Editors note: This blog is based on the presentation of the 65 trial at the Critical Care Reviews conference in Belfast. We will add more data, and be able to add a more detailed critical


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