CAP23

JC : Paracetamol, NSAID’s or both in MSK trauma. St.Emlyn’s

Is paracetamol alone enough for pain after minor musculoskeletal injury? This 2017 review examines a randomised non-inferiority trial comparing paracetamol, diclofenac and their combination. It explores pain outcomes, trial design and exclusions, including why the findings cannot simply be extended to fractures or all painful injuries.

JC : Paracetamol, NSAID’s or both in MSK trauma. St.Emlyn’s Read More

Management of paracetamol therapeutic excess in the ED. St.Emlyn’s.

How does repeated excess paracetamol taken for pain differ from other overdose presentations? This 2017 discussion explores therapeutic excess, risk assessment and the consequences for admission. It repeatedly stresses checking current TOXBASE or local toxicology guidance, rather than relying on the historical thresholds described in the post.

Management of paracetamol therapeutic excess in the ED. St.Emlyn’s. Read More

Is Ketofol the milk of human kindness for procedural sedation. St.Emlyn’s

Does combining ketamine and propofol improve procedural sedation compared with propofol alone? This 2016 appraisal examines a systematic review’s complication findings, questioning how differences in patients, procedures and drug regimens—and limited information on sedation success—affect its relevance to emergency departments.

Is Ketofol the milk of human kindness for procedural sedation. St.Emlyn’s Read More

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