Tag: sepsis

JC: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock. The ACTS Randomized Clinical Trial St Emlyn’s

Back in 2017 the sepsis world had a rather strong reaction to a paper published by Paul Marik that suggested that a combination of steroid, vitamin C and Thiamine could cure sepsis. The data, published

JC: Critical Care Reviews day 2. #CCR20. St Emlyn's

In addition to the presentation of the VITAMINS trial and the PEPTIC trial we also saw a number of other papers presented. These are listed below, but have not been fully critically appraised. We’ll leave

The VITAMINS trial

JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis. St Emlyn's

You may remember the controversy about Paul Marik’s suggestions that a combination of Vitamin C, steroids and Thiamine (sometimes known as HAT​1​) is a cure all for sepsis. There were some rather dramatic claims that

JC: The IHME study on the global burden of sepsis. St Emlyn's

Editors note: This blog is based on the presentation of this trial at the Critical Care Reviews conference in Belfast. We will add more data, and be able to add a more detailed critical appraisal

JC: The 65 trial. Targeting MAP in sepsis. St Emlyn's at #CCR20

Editors note: This blog is based on the presentation of the 65 trial at the Critical Care Reviews conference in Belfast. We will add more data, and be able to add a more detailed critical

SMACC Day 2 morning sessions: St Emlyn’s

After a fabulous first day and a very good dinner at the Quay restaurant in Sydney we are back at the ICC for day 2. The big announcement of the day was the news about

World Sepsis Conference: #wsc18 an Online, Free, #FOAMed style conference this week. 5th/6th September.

There is no doubt that I love a conference. I’ll freely admit this. I love the travel, the connections and the opportunity to learn, but I also have anxieties about the inequality of conferences, notably

JC: The End of the ‘Roid? ADRENAL

So another year, another Critical Care Reviews meeting. Rob is doing an absolutely fantastic job with these, inviting lead authors from major critical care trials to present and defend their work. In fact, this is


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