A December 2020 appraisal of PRIEST’s evaluation of risk scores in emergency department patients with suspected COVID-19. It examines the balance between sensitivity and specificity, differences between predicting death and organ support, and why the population in which a score is tested matters.
Risk stratification in the ED for COVID19 patients: The PRIEST study. St Emlyn’s Read More
Before the fuller tocilizumab trial reports, Dan Horner examined the conflicting evidence available in December 2020. This appraisal considers biological plausibility, early REMAP-CAP announcements, adverse effects and the difficulty of discussing an experimental treatment when media coverage runs ahead of the data.
Tocilizumaybe? Immune modulation in COVID-19 Read More
Simon Carley and Rick Body discuss the strengths and limitations of COVID-19 testing in December 2020. The episode and accompanying links explore PCR, LAMP, rapid testing and lateral flow tests, alongside the FALCON/CONDOR programme evaluating new diagnostics.
Understanding COVID-19 testing with Rick Body. St Emlyn’s Read More
A November 2020 appraisal of the PLACID convalescent plasma trial in moderately unwell hospitalised patients with COVID-19 in India. It explores the lack of demonstrated clinical benefit, variation in usual care and antibody levels, and why larger trials were still needed.
JC: Convalescent plasma in COVID 19 patients. Read More
How should trainee experience shape emergency medicine research priorities? Rob Hirst describes TERN’s 2020 priority-setting project, explains the Delphi consensus process and considers why the questions trainees encounter may differ from those emphasised by other professional groups.
Research, trainees and prioritisation in UK emergency medicine. Read More
How well do guidelines identify meningococcal disease in children with fever and a non-blanching rash? Natalie May reviews the PiC study, examining sensitivity, overtreatment and what happened when clinicians departed from protocols, while keeping the study population and limitations in view.
JC: Spot the Difference, what can we do about petechiae? St Emlyn’s Read More
A November 2020 introduction to the first CODA Zero online sessions. The post highlights global perspectives on sepsis and COVID-19, alongside a discussion of gender equality that moves from recognising problems to ideas for action within the healthcare community.
CODA Zero episodes now open access. Read More
Trauma and coagulopathy are the focus of Iain and Simon’s October 2020 round-up. The episode notes link to appraisals of prehospital TXA, plasma in traumatic brain injury, targeted transfusion testing and other clinical topics, alongside a conversation about coping with the second pandemic wave.
Podcast – October 2020 Monthly Round Up Read More
