Why can a cheap, straightforward treatment struggle for attention alongside more dramatic interventions? Reflecting on tranexamic acid after CRASH-2 in 2012, Simon Carley questions the appeal of expensive or technically demanding therapies and asks how clinicians can close the gap between evidence and routine practice.
Tranexamic acid needs a make over Read More
How should the early risks of stroke thrombolysis be weighed against later functional outcomes? This 2012 journal club debates IST-3, contrasting early mortality and bleeding with six-month survival and independence, and examining how the trial’s results are presented and interpreted.
JC: Thrombolysis in Acute Stroke – IST3 Read More
Why can a correct answer still lose marks in a critical-appraisal exam? In this 2012 guide to the former FCEM format, Simon Carley discusses reading the question, practising with papers, explaining statistics clearly and constructing an abstract whose objectives, results and conclusions fit together.
The Critical Appraisal FCEM exam Read More
How should an emergency clinician assess a request for HIV post-exposure prophylaxis after sexual exposure? This 2012 discussion explores the guidance available at the time, individual exposure risk, adherence and timely specialist support, emphasising a systematic and sensitive consultation.
Post Exposure Prophylaxis Read More
