Rich Carden reviews a cohort study linking post-intubation hypotension with 30-day mortality in severe traumatic brain injury. The appraisal considers what the association means for prehospital anaesthesia and how far observational findings can guide practice.
Is post-induction hypotension harmful in traumatic brain injury? Read More
Paracetamol poisoning is an uncommon, but not rare, event in children. The treatment of choice is NAC. Should we be giving them the SNAP protocol?
Make it SNAPpy! Paracetamol overdoses in teenagers Read More
The FiiRST-2 randomised trial compared fibrinogen and prothrombin complex concentrate with plasma in trauma patients needing massive transfusion. No significant benefit was found.
Factors in the Initial Resuscitation of Patients With Severe Trauma – The FiiRST-2 Trial Read More
The Ket-Mid trial tested adding ketamine to midazolam for initial treatment of paediatric convulsive status epilepticus. We review its seizure-control findings and explain why the single-centre setting, delayed treatment and differences from UK practice make the author cautious about changing care.
JC: Ketamine or Midazolam as first choice for Paediatric Status Epilepticus? St Emlyn’s Read More
A review of the GECCO (Global health and emergency care) research summit in the UK bringing together expert speakers, panelists and workshop facilitators.
GECCo’s Global Health & Emergency Care Research Summit, July 2025 Read More
Could stellate ganglion block have a role during refractory cardiac arrest? This appraisal examines a scoping review of 32 reported cases, the rationale for the technique and why publication bias and other treatments make the apparent benefits difficult to interpret.
JC: Intra-arrest Stellate Ganglion Block Read More
How should we assess children with one or two positive PECARN abdominal trauma criteria? This appraisal examines a secondary analysis of the prediction rule, the different risks associated with individual findings and the continuing role of clinical judgement and repeated assessment.
Evaluating the PECARN Abdominal Trauma Rule in the grey zone…. Read More
Can arterial lines be placed during cardiac arrest in the ED, and what can they tell us? This appraisal reviews one department’s experience, the selection bias in its small intervention group and why feasibility does not establish better patient outcomes.
Arterial Line Placement During Cardiac Arrest: The ED experience. Read More
