Tag: dom9

JC: Vitamin C and sepsis (again). St Emlyn’s

The story of vitamin C in sepsis is fascinating. There was a great deal of controversy around what became known as the Marik protocol (after Prof. Paul Marik). The protocol included the use of vitamin

Differential prescribing of TXA by gender. St Emlyn’s

Tranexamic acid in trauma is a well-established standard of care in most mature trauma systems. The two major trials of TXA, CRASH 2 and 3 suggest a small but important decrease in mortality for patients

How to become a sub-specialist in emergency care research. St Emlyn’s

At a basic level emergency care clinicians should be trained in Good Clinical Practice and able to recruit to trials. However some will want to make research into a larger part of their work. This

JC: The RePHILL trial. St Emlyn’s

This week we see the publication of the RePHILL trial. This is something we have been looking forward to for some time. A randomised controlled trial of the use of packed red cells, LyoPLAS and

Designer medicine for suspected DVT: the 4D study. St Emlyn’s

Do you want to halve your ultrasound referral rate for suspected Deep Vein Thrombosis? You do? How marvellous. Reducing referral rates from ED for a specialist test like vascular sonography can have multiple benefits for

James Lind research priority setting. St Emlyn’s

Back in 2015 the James Lind organisation helped us set research priorities for emergency medicine in the UK. St Emlyn’s were proud to support the process at that time as we are advocates for open,

JC: Etomidate vs. Ketamine for emergency intubation. St Emlyn’s

Just a quick review this week as this is a paper published back in December that has been superbly reviewed already over on the SGEM. However, it’s an interesting topic and one that has been

JC: Should we use calcium in out of hospital cardiac arrest? St Emlyn’s

A trial published in JAMA asks exactly this question, the full text can be found here. The abstract is below, but as we always say, please read the full paper yourself. Previous studies have shown

JC: More on pulse oximetry and racial bias. St Emlyn’s

This week we are reviewing a paper on the accuracy of pulse oximetry in patients being assessed for ECMO. This is an interesting group as they represent and extremely unwell group of patients where small

JC: The REST trial. St Emlyn’s

Some years ago I remember speaking to a rather well known intensivist who was advocating for the extracorporeal removal of CO2 in ICU patients. His logic was that in patients with hypoxic lung failure we