Epi 289: Refractory VF, Double Sequential Defibrillation, and the Future of Cardiac Arrest

In this episode, we talk to Sheldon Cheskes about the evolving science of cardiac arrest, with a focus on refractory and recurrent ventricular fibrillation. We explore the evidence behind double sequential external defibrillation (DSED), how it compares to standard defibrillation, and what the DOSE VF trial has changed in practice. It’s about understanding why defibrillation fails, how vector and energy delivery matter, and when a different approach might improve outcomes.

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2026 PE Guidelines

Pulmonary embolism (PE) is one of those diagnoses that finds its way into a lot of differential diagnoses. In the era of reasonably easy-but-occasionally-argue-with-radiologist to get CTPAs, the diagnosis has increased. An

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