All posts by Simon Carley

Simon Carley MB ChB, PGDip, DipIMC (RCS Ed), FRCS (Ed)(1998), FHEA, FAcadMed, FRCEM, MPhil, MD, PhD is Creator, Webmaster, owner and Editor in Chief of the St Emlyn’s blog and podcast. He is visiting Professor at Manchester Metropolitan University and a Consultant in adult and paediatric Emergency Medicine at Manchester Foundation Trust. He is co-founder of BestBets, St.Emlyns and the MSc in emergency medicine at Manchester Metropolitan University. He is an Education Associate with the General Medical Council and is an Associate Editor for the Emergency Medicine Journal. His research interests include diagnostics, MedEd, Major incidents & Evidence based Emergency Medicine. He is verified on twitter as @EMManchester

JC: The BASICS trial. 0.9% saline vs balanced solution. Does it matter?

I’ll admit that my long term clinical practice has been to prefer balanced solutions (in my case Hartmans) over 0.9% saline in the management of the critically ill patient. It’s a topic we’ve blogged and

JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial. St Emlyn’s

I remember back at the beginning of the pandemic when we were seeing lots of patients arriving in the ED in extremis. The now familiar picture of the deeply hypoxic patient with terrible chest X-rays

June and July 2021 Podcast round up. St Emlyn’s

Our regular round up of the best of the blog from June and July 2021. Some Aural sunshine for you in these Summer months (in the Northern Hemisphere at least). Links to the blog posts

targeted temperature management

JC: The TTM2 trial. Normothermia or hypothermia post cardiac arrest.

A quick update on an TTM2 trial published in the NEJM last month. As part of the chain of survival it’s important to optimise the post resuscitation phase, primarily to preserve neurological function as this

REGN monoclonal antibodies work in selected hospitalised COVID-19 patients. St Emlyn’s

We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. In the last month the RECOVERY trial has

May 2021 podcast

May 2021 Podcast round up. St Emlyn’s

Our regular round up of the blog highlights in podcast form as hosted by Ian and Simon.

JC: Aspirin is not effective for hospitalised COVID19 patients. St Emlyn’s

We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. This week the RECOVERY trial has released the

April 2021 podcast

April podcast round up: St Emlyn’s

Our regular round up of the best of the blog from April 2021. Not as many posts as usual this month as we were busy with the RCEM CPD conference, but really pleased to get

Manchester Arena Bombing data now published in EMJ. St Emlyn’s

Next month we will mark the fourth anniversary of the Manchester Arena Bombing on the 22nd May. As you will remember Salman Ramadan Abedi detonated an improvised device in the foyer of an Ariana Grande

Bayes belief and bias

Bayes and Belief: How pre-review belief influences critical appraisal. St Emlyn’s

I’ve been reflecting on why there is disagreement about how influential new evidence is to clinical practice in the last year or so. COVID-19 has shown that the thresholds for what we believe and when