Iain and Simon revisit February 2021 on the St Emlyn’s blog and podcast. The accompanying article links cover TIA risk assessment, proposed emergency care standards, tocilizumab evidence, TXA for epistaxis and conversations with patients about COVID-19 risk.
Podcast – February 2021 Monthly Round Up Read More
Does topical tranexamic acid reduce the need for nasal packing when initial epistaxis treatment has failed? This 2021 appraisal of the NoPAC trial examines its negative result, the importance of preceding first aid and vasoconstrictors, and limits to generalising across different types of bleeding.
JC: Epistaxis – The NoPAC trial – Does TXA work? Read More
What does STAAMP add to the evidence for prehospital tranexamic acid after trauma? This 2020 appraisal examines the lack of a clear overall mortality benefit, recruitment and power limitations, safety findings and the caution needed when interpreting encouraging timing, shock and dosing subgroups.
JC: Should we rubber STAAMP prehospital TXA? Read More
Could intramuscular tranexamic acid be useful when intravenous delivery is difficult? This 2020 review examines a small pharmacokinetic study in trauma patients who had already received IV TXA, distinguishing encouraging absorption data from evidence of improved outcomes or effectiveness as an initial dose.
JC: Can we give tranexamic acid (TXA) via the IM route? St Emlyn’s Read More
What did HALT-IT establish about tranexamic acid for gastrointestinal bleeding? This 2020 appraisal examines the lack of a mortality benefit and the increased venous thromboembolism and seizure signals, alongside questions about recruitment, treatment timing and the trial’s primary outcome.
JC: Halt! It’s not time for TXA! Or is it? HALT-IT results at St Emlyn’s Read More
A review of the CRASH-3 trial and whether tranexamic acid (TXA) is of benefit in traumatic brain injury patients.
Tranexamic Acid (TXA) in Head Injury: CRASH-3 results Read More
Administration of tranexamic acid (TXA) is integral part of the management for major trauma patients in the UK. It is deemed such an important aspect that its administration is used
JC: Does earlier TXA save lives? St.Emlyn’s Read More
Here at St.Emlyn’s we are big fans of Tranexamic Acid in trauma. We believe that it makes a difference to overall mortality in patients likely to be bleeding and also
JC: Tranexamic acid – does the evidence stack up? Read More
