Tag: journal club

JC: Convalescent plasma in COVID 19 patients.

This month the BMJ has published a trial on the use of convalescent plasma in the treatment of admitted patients with COVID-19 (the PLACID trial). Convalescent plasma therapy basically takes plasma, together with antibodies from

JC: ISARIC. Possibly The Best COVID-19 Risk Prediction Tool To Date

Has your department been relying on clinical gestalt to risk stratify patients, perhaps using something you heard or read about in a short paper (perhaps Twitter), maybe something like post-exertional oxygenation has caught your eye,

JC: TXA in severe head injury. St Emlyn’s

Our post on the CRASH-3 trial, an RCT examining the use of TXA in head injury, was arguably our most controversial of 2019 (1). Our view was that the evidence was not entirely definitive, but

Covid-19 Journal Club: The Director’s Cut #6

The Emergency Medicine Academic Group based out of Leicester have given us another fantastic directors cut. Check out their work here! Professor Tim Coates and Dr Mohammed Elwan have searched every COVID-19 publication, and summarised

JC: Does post exposure prophylaxis (with HCQ) work in Covid-19?

The utility of hydroxychloroquine in the management of Covid-19 often seems to be more of a political than a medical debate. Many politicians, journalists, hacks, and a whole range of social media experts have an

JC: Haloperidol for Headaches. St Emlyn’s

Lone acute severe headaches are a common and sometimes complex presentation to all Emergency Departments. There are obviously life threatening causes of a headache that we rule out with judicious history taking and examination. The

Top 10 trauma papers 2019-2020 for Liverpool Trauma Seminars. St Emlyn’s

This week I am presenting (virtually) at the Liverpool Trauma Seminar. This is a new initiative that aims to provide a multispeciality, multidisciplinary trauma conference in the North West of England. It’s run out of

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

JC: Halt! It’s not time for TXA! Or is it? HALT-IT results at St Emlyn’s

If you’re any kind of emergency care aficionado, you probably worship at the altar of tranexamic acid (TXA). With data showing more favourable outcomes from its use in traumatic bleeding​(1)​, post-partum haemorrhage​(2)​, maybe traumatic brain

COVID-19 Journal Club: The Director’s Cut #5

We have searched every COVID-19 publication, and summarised the literature of everything published in the last week. We have highlighted those papers that will be of interest to EM clinicians on the front line. This


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