Category: Science

All things relating to science and technology.

Colchicine

Cochicine does not improve mortality in COVID19. St Emlyn’s

This week the RECOVERY trial has released the first results from the Colchicine arm of the trial. We await the pre-print and the peer reviewed paper, but we are already very familiar with the trial

Oxygen targets in critical care: The HOT-ICU trial. St Emlyn’s

Oxygen targets in critically ill/injured patients has been something we’ve talked about on the blog before. In general the evidence to date has suggested that the routine prescription of oxygen to patients is unhelpful and

The Emerging Evidence for a Genetic Susceptibility to Severe Covid-19. St Emlyn’s

A defining feature of the COVID-19 pandemic has been the wide spectrum of clinical presentations, ranging from asymptomatic viremia to life-threatening illness.1 Factors such as advancing age and co-morbid status have been shown to strongly correlate

The ‘Roid’ to Recovery? REMAP-CAP @ St Emlyn’s

This week JAMA published three important trials on the use of steroids in patients with severe COVID-19, with an additional cherry on top; a subsequent inclusive meta-analysis (totalling 7 RCTs and 1703 patients) from the

Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s

We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A few weeks ago a press

Covid19: Why we need Evidence Based Medicine (EBM) more than ever during a pandemic. St Emlyn’s

Evidence based medicine (EBM) is one of the four pillars of St Emlyn’s. We are usually pretty sceptical about adopting treatments without high quality evidence publishfred in a decent journal and with critical appraisal. Covid19

Covid19: Lessons from Sports and Exercise Medicine. St Emlyn’s

We got together with Dr Nathan Lewis and Dr John Rogers to discuss how lessons from Sports and Exercise Medicine might help during the Covid19 pandemic.Click on the podcast link below The main messages for

JC: AVP in Haemorrhagic Shock. St Emlyn’s

Blood product transfusion can be lifesaving for patients who have suffered major trauma, but the associated side-effects and risks, mean that most people would agree that less is more. This paper by Sim et al

JC: Top 10 papers 2018-2019 for #RCEM Annual Scientific Conference. St Emlyn’s

This week the St Emlyn’s team is in Gateshead for the Royal College of Emergency Medicine’s annual scientific conference. This year I’ve been tasked with putting together the top 10 (plus 1) papers of the

July podcast 2019 St Emlyn's

July 2019 Podcast Round Up: St Emlyn’s

Our regular podcast review of the best of the blog from July 2019

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