A January 2021 appraisal of REMAP-CAP's early tocilizumab and sarilumab findings in critically ill patients with COVID-19. Dan Horner examines organ support and survival outcomes, strict eligibility criteria and the uncertainties that remained as the results moved rapidly into policy and public discussion.
Rick Body and colleagues discuss the COVID-19 vaccine evidence as the UK rollout gathered pace in January 2021. The episode notes link to the Moderna, Oxford and Pfizer trials, providing a record of the science and questions informing that early stage of vaccination.
Philosophy of Emergency Medicine
How can academics make their work easier to find, understand and discuss online? Simon Carley offers a practical introduction to professional profiles, collaboration, adapting research for different media and curating an online presence, while considering the risks of echo chambers and amplification.
A clinical overview of Ludwig's angina, from dental infection and deep neck anatomy to recognition and airway risk. The article reviews presentation, imaging and management challenges, with particular attention to how swelling can complicate assessment and securing the airway.
Esther Murray and colleagues explore moral injury and the psychological impact of working through COVID-19. This video discussion considers recognition, prevention and support, emphasising honest conversations and the importance of feeling heard when difficult experiences challenge clinicians' values.
A December 2020 review of RECOVERY's lopinavir/ritonavir results in hospitalised patients with COVID-19. It discusses the lack of demonstrated benefit, the limits of extrapolating to earlier disease and how adaptive platform trials made rapid evaluation of proposed treatments possible.
Practical perspectives on trauma care and team leadership.
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