When things get exciting: Thoughts on the recent EMCRIT episode on serotonin syndromes.
In this emergency medicine toxicology blog, Gregory Yates reflects on a recent EMCRIT podcast episode discussing serotonin syndrome, neuroleptic malignant syndrome (NMS), and other hyperthermic drug reactions. The post highlights the diagnostic importance of neuromuscular findings such as clonus, tremor, and hyperreflexia, as outlined in the Hunter criteria. It also critiques the limitations of relying solely on drug history and explores the inter-rater variability in neurological examinations for movement disorders. With real-world cases from Virchester, the piece underlines the risks of misdiagnosis — particularly the danger of using antipsychotics in the wrong toxidrome. The takeaway: thorough neurological assessment is crucial, and clinicians should be cautious when interpreting overlapping syndromes.
When things get exciting: Thoughts on the recent EMCRIT episode on serotonin syndromes. Read More