What can a Japanese surveillance study tell us about the safety of fomepizole in suspected methanol and ethylene glycol poisoning? Greg Yates reviews the reported adverse reactions, the study’s limitations and the uncertainty when the initial diagnosis is wrong.
Toxic alcohol poisoning: What do we know about fomepizole, methanol and ethylene glycol? Read More
What happens after an overdose of a GLP-1 agonist such as semaglutide? This appraisal examines US poison-centre data on dosing errors, reported symptoms and hypoglycaemia, and considers how incomplete reporting and broad outcome definitions limit what the study can tell emergency clinicians.
Can symptoms identify who needs endoscopy after a caustic ingestion? Greg Yates examines a retrospective study of corrosive exposures, focusing on how significant injury was defined, the treatment of pain in symptom classification and the missing follow-up that limits reassurance from its findings.
When is emergency endoscopy required for caustic ingestions? Read More
Could intranasal ketorolac offer an alternative to intravenous analgesia for renal colic? This appraisal examines a randomised trial comparing the two routes, its pain outcomes and methodological limitations, including how the choice of comparator affects its relevance to UK practice.
Intranasal ketorolac in renal colic Read More
What happens to older patients who spend the night in the emergency department awaiting a ward bed? This appraisal examines a prospective cohort study linking overnight ED stays with in-hospital mortality, while considering confounding and the importance of comfort and dignity.
Are long waits in A&E lethal for elderly patients? Read More
