Tag: rp4

Bayes belief and bias

Bayes and Belief: How pre-review belief influences critical appraisal. St Emlyn’s

I’ve been reflecting on why there is disagreement about how influential new evidence is to clinical practice in the last year or so. COVID-19 has shown that the thresholds for what we believe and when


JC: Real world cricothyroidotomy experience. St Emlyn’s

Cricothyroidotomy is a procedure that worried many emergency physicians. Partly because it’s a rare procedure, but also because we are likely to embarking on it at a time when things are ‘going wrong’. The most

Can a prediction model improve major trauma triage? St Emlyn’s

Ed – Tom Shanahan (here in Virchester) recently published a paper on whether a Dutch prediction model is better at identifying major trauma patients than existing methods. The publication provoked an interesting debate on Twitter

NoPAC study

JC: The NoPAC trial. TXA does not work for epistaxis. St Emlyn’s

Over the years we have had more than a passing interest in tranexamic acid. In part because we have been involved in some of the research, recruiting to trials, or acting as principal investigators, but

JC: Early plasma use in traumatic brain injury. St Emlyn’s

There seems to be a lot of really interesting papers on Traumatic Brain Injury (TBI) this year. A welcome relief from COVID 19 perhaps but also a reminder that other pathologies exist and that TBI

JC: Should we rubber STAAMP prehospital TXA?

This post is co-published with our friends at REBEL EM. Background: It almost seems that when it comes to the use of the antifibrinolytic agent tranexamic acid (TXA) in trauma, one argument has just been

JC: Blood Products in Trauma – What’s the Best (I)TACTIC?

Bleeding trauma patients present a couple of challenges to us in the Emergency Department. Increasingly, our aging population continues to engage in energetic daily pursuits while increasing numbers are prescribed newer direct oral anticoagulant treatments

JC: Can we give tranexamic acid (TXA) via the IM route? St Emlyn’s

Tranexamic Acid (TXA) is a mainstay of trauma management. CRASH 2 (2) demonstrated its effectiveness in bleeding patients and CRASH 3 (1,5) (in my opinion) showed that we should also be using it in mild/moderate

JC: TXA in severe head injury. St Emlyn’s

Our post on the CRASH-3 trial, an RCT examining the use of TXA in head injury, was arguably our most controversial of 2019 (1). Our view was that the evidence was not entirely definitive, but

Top 10 trauma papers 2019-2020 for Liverpool Trauma Seminars. St Emlyn’s

This week I am presenting (virtually) at the Liverpool Trauma Seminar. This is a new initiative that aims to provide a multispeciality, multidisciplinary trauma conference in the North West of England. It’s run out of