Does extracorporeal carbon dioxide removal make lower-volume ventilation safer or more effective? This 2021 review of the REST trial examines 90-day mortality, adverse events and the uncertainty left by early stopping in patients with acute hypoxaemic respiratory failure.
A 2021 appraisal of early CT coronary angiography for patients with suspected acute coronary syndrome. It examines a UK randomised trial's patient outcomes, use of invasive angiography and limitations, asking whether routine CTCA is justified in this selected population.
Simon Carley's selection of ten trauma papers for the 2021 Trauma Care UK conference spans haemorrhage control, airway intervention and traumatic brain injury. The review considers what the findings add to practice and where trial design or uncertainty limits their interpretation.
Does fluid choice affect outcomes in intensive care? This 2021 appraisal of BaSICS compares Plasma-Lyte with 0.9% saline, examining 90-day mortality, infusion rates and subgroup findings while cautioning against generalising to every balanced solution or patient setting.
Does cooling to 33°C improve outcomes after out-of-hospital cardiac arrest? This 2021 review of TTM2 compares hypothermia with actively managed normothermia, examining survival, neurological outcomes, adverse events and why fever control should not be confused with leaving temperature unmanaged.
What can point-of-care ultrasound add when a patient presents in shock? This 2021 review explores ultrasound protocols, diagnostic accuracy and patient outcomes, questioning a uniform scanning approach and considering how clinical context and pre-test probability can guide a focused examination.
Practical perspectives on trauma care and team leadership.
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