Can head-up positioning combined with mechanical CPR and an impedance threshold device improve cardiac arrest outcomes? This 2022 appraisal examines an observational comparison, explaining why differences between cohorts and exploratory analyses limit the conclusions it can support.
A 2022 overview of severe traumatic brain injury, centred on preventing secondary injury before and during specialist transfer. Dan Horner discusses tiered management and unresolved questions about osmotherapy, blood-pressure targets and brain tissue oxygen monitoring.
A 2022 review of UK prehospital blood-product and calcium replacement protocols. The article explores variation between services, the limits of survey evidence and unanswered questions about calcium timing and dose, distinguishing associations with poor outcomes from evidence of treatment benefit.
Natalie May reports from day three of ICEM 2022 in Melbourne. Lessons from major incidents in Manchester, New Zealand, Beirut and Tonga sit alongside sessions on prehospital retrieval, human factors and shared leadership.
A 2022 journal club examining the LOVIT trial of intravenous vitamin C in ICU patients with sepsis receiving vasopressors. It reviews death and persistent organ dysfunction outcomes, and reflects on how early enthusiasm for a treatment should be tested by stronger evidence.
A 2022 appraisal of sex differences in tranexamic acid use after trauma. The review separates analyses of treatment effectiveness from registry data on prescribing, considering differences between patient groups and what the findings can explain about unequal treatment and where uncertainty remains.
Practical perspectives on trauma care and team leadership.
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