Evidence-Based Medicine

A June 2020 appraisal of the RECOVERY dexamethasone preprint in hospitalised patients with COVID-19. The review examines mortality findings in patients receiving oxygen or ventilation, recruitment and generalisability, and the difficulties of assessing important research first announced through a press release.

Ten COVID-19 papers selected for emergency clinicians in June 2020. The team reviews paediatric inflammatory illness, testing, vaccine planning, staff wellbeing and the pandemic's wider health effects, explaining where early studies and commentary leave important uncertainties.

The reading list for the 18 June 2020 COVID-19 journal club with Katrin Hruska. Topics include lung ultrasound, paediatric inflammatory illness, bystander CPR and health inequalities, alongside the first RECOVERY announcement and the implications of recent research retractions.

Iain and Simon review May 2020 on St Emlyn's, including COVID-19 research discussions and venous thromboembolism resources. The written episode notes also connect global health, race and inequality with reflections on privilege and the perspectives emergency clinicians bring to their work.

An early June 2020 response to RECOVERY's announcement that hydroxychloroquine had not shown benefit in hospitalised patients with COVID-19. Simon Carley explains the platform trial design and why the limited information released at that stage still required a full critical appraisal.

The recording and reading list from the 26 May 2020 COVID-19 journal club, with guest Kelly Ann Janssens. The panel examines the preliminary remdesivir report, testing uncertainty, emergency department diagnosis and paediatric transmission in the context of the evidence available at that time.