A 2022 journal club on the FAKT trial of fentanyl during rapid sequence intubation with ketamine and rocuronium. It separates the primary blood-pressure outcome from secondary findings and considers how patient selection and drug timing affect interpretation.
JC: Fentanyl as an adjunct in RSI. Does it affect haemodynamic stability? St Emlyn’s Read More
Can head-up positioning combined with mechanical CPR and an impedance threshold device improve cardiac arrest outcomes? This 2022 appraisal examines an observational comparison, explaining why differences between cohorts and exploratory analyses limit the conclusions it can support.
A 2022 overview of severe traumatic brain injury, centred on preventing secondary injury before and during specialist transfer. Dan Horner discusses tiered management and unresolved questions about osmotherapy, blood-pressure targets and brain tissue oxygen monitoring.
TBI: The Final Frontier… Read More
A 2022 review of UK prehospital blood-product and calcium replacement protocols. The article explores variation between services, the limits of survey evidence and unanswered questions about calcium timing and dose, distinguishing associations with poor outcomes from evidence of treatment benefit.
More on Calcium and blood products in trauma. St Emlyn’s Read More
Iain and Simon review highlights from the St Emlyn’s blog in this combined June and July 2022 podcast round-up.
Podcast – June/July 2022 Monthly Round Up Read More
A 2022 review of the RECOVERY trial’s baricitinib comparison in hospitalised patients with COVID-19. It explains the adaptive trial design, examines 28-day mortality and considers the uncertainty about longer-term outcomes alongside other immunosuppressive treatments.
Baricitinib for hospitalised COVID19 patients. St Emlyn’s Read More
A critical look at the EXIT study’s 2022 consensus statements on extrication after road traffic collisions. The review considers self-extrication, gentle handling and time-critical care, alongside questions about expert selection and the modified Delphi process used to reach agreement.
The EXIT study extrication consensus statements. St Emlyn’s Read More
A 2022 appraisal of the FORCE trial comparing an offer of bandaging with rigid immobilisation for children’s distal radius buckle fractures. It examines pain outcomes, treatment preferences and how the trial design reflects conversations with children and families.
The FORCE study: St Emlyn’s Read More
