Jack Lyon examines the evidence for sedation in prehospital acute behavioural disturbance, including ketamine, midazolam and droperidol. The review considers effectiveness, adverse events and the limitations of the studies, alongside the skills and resources needed to manage complications.
Could peer support in the ED help people engage with treatment after an opioid overdose? Greg Yates reviews a New Jersey programme, examining improved treatment engagement, the absence of a significant reduction in repeat overdose and the limits of observational evidence.
What do trials of smoking cessation in the ED show? Greg Yates reviews the evidence for interventions that include nicotine replacement therapy, the variation in treatment effects and the unresolved questions about resources, follow-up and the emergency department's role.
Paracetamol poisoning is an uncommon, but not rare, event in children. The treatment of choice is NAC. Should we be giving them the SNAP protocol?
Three research reviews explore goal-directed chest compressions, ventilation during cardiac arrest and cerebral oximetry. Greg Yates considers what animal and human studies contribute to physiologically guided resuscitation, and where further evidence is needed.
Can bedside mixtures provide a reliable calcium gel for hydrofluoric acid burns? Greg Yates reviews a laboratory study of viscosity and calcium concentration, and considers what its findings mean for stocking commercial antidote supplies in emergency departments.