The 2015 ProMISe trial compared early goal-directed therapy with usual care for patients with septic shock in UK hospitals. This appraisal examines mortality, treatment overlap and patient selection, asking what the findings added to ARISE and ProCESS and which questions about individualised care remained unresolved.
A guide to the changes introduced in the 2015 APLS trauma update, with an accompanying podcast. Simon Carley discusses haemorrhage control, cervical spine management, vascular access, imaging and pain relief, alongside implications for instructors and areas where contemporary guidance differed.
Iain Beardsell and Simon Carley discuss opioid overdose in this 2015 podcast and written review. They examine recognition beyond stereotyped presentations, resuscitation, the challenges of naloxone reversal and ongoing monitoring, while also considering co-ingestion, complications and patients’ wider mental health and social needs.
How can emergency clinicians keep up with research without being overwhelmed? This 2015 guide explains the team’s approaches to personalised PubMed alerts, journal and topic searches, RSS readers and shared coverage with colleagues, while emphasising that online appraisals should support reading the original literature.
What can a long-running intubation registry tell us about airway care in the emergency department? This 2015 journal club examines Scottish data on intubation success, collaboration with anaesthetists and training, while considering missing records and the limitations of combining practice across fourteen years.
Karim Brohi discusses vascular injury in a short podcast recorded at the 2014 London Trauma Conference. The accompanying introduction highlights recognising the ischaemic injured limb, questioning assumptions about hard and soft signs, and the role of interventional radiology in major trauma care.