Does cooling to 33°C improve outcomes after out-of-hospital cardiac arrest? This 2021 review of TTM2 compares hypothermia with actively managed normothermia, examining survival, neurological outcomes, adverse events and why fever control should not be confused with leaving temperature unmanaged.
What can point-of-care ultrasound add when a patient presents in shock? This 2021 review explores ultrasound protocols, diagnostic accuracy and patient outcomes, questioning a uniform scanning approach and considering how clinical context and pre-test probability can guide a focused examination.
A review of the 2021 anaphylaxis guideline update, linking the underlying physiology with emergency treatment. Iain Beardsell discusses early intramuscular adrenaline, the changing roles of antihistamines and steroids, and the guideline's approach to observation and discharge after a response to treatment.
A March 2021 appraisal of anticoagulation trials in critically ill patients with COVID-19. Simon Carley and Dan Horner examine therapeutic-dose versus usual-care thromboprophylaxis, organ support outcomes and bleeding, explaining why the findings cannot simply be extended to ward patients or treatment of confirmed thrombosis.
A March 2021 review of the RECOVERY convalescent plasma preprint in hospitalised patients with COVID-19. It examines the absence of a survival benefit, donor antibody testing and subgroup findings, and reflects on why promising treatments still need randomised evidence.
What can a specialist prehospital service teach us about a rare emergency airway procedure? This review of London Air Ambulance's 20-year cricothyroidotomy experience separates procedural success from patient survival and considers the implications for training, preparation and interpreting retrospective data.
Practical perspectives on trauma care and team leadership.
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