What is the difference between levobupivacaine and bupivacaine, and does it matter for a child’s nerve block? This 2012 discussion explains stereoisomers, examines the evidence behind claims of reduced cardiac toxicity and questions how well adult and animal findings apply to small paediatric doses.
Chirocaine vs Bupivicaine – Through the Looking Glass Read More
Should superficial venous thrombosis be observed or treated with anticoagulation? This 2012 discussion considers what ultrasound adds, unpacks the composite outcome in CALISTO and weighs treatment benefits against bleeding and burden, emphasising the importance of explaining uncertainty when making decisions with patients.
Superficial Venous Thrombosis: watch and wait or anticoagulate? Read More
Should patients in below-knee plaster casts receive heparin to prevent venous thromboembolism? This 2012 reflection examines a published evidence review, contrasting the frequency of detected DVT with rarer serious outcomes and asking how treatment harms and individual risk should influence practice.
Should POPs be mixed with Heparin? Read More
Does ondansetron help children with gastroenteritis tolerate oral rehydration, and how should concerns about cardiac rhythm be interpreted? This 2012 appraisal examines the evidence behind an FDA warning, questioning how studies in anaesthetic settings apply to emergency care and weighing potential benefit against uncertainty about harm.
Ondansetron in vomiting children Read More
