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Does reaching hypothermia sooner after cardiac arrest improve outcomes? This 2012 journal club examines an observational study of cooling times, using its results to explain relative risk, absolute risk and number needed to treat while questioning whether confounding could explain the apparent benefit of later cooling.

Can case conferences help teams learn without becoming an exercise in blame? Rick Body uses a hypothetical asthma emergency to explore constructive reflection, fair feedback and the importance of recognising good care alongside opportunities to improve.

St Emlyn's prepared for SimWars at SMACC 2013 in Sydney with enthusiasm and a playful concern about Australian wildlife. This 2012 preview introduces the team's plans and a pre-competition session with Minh le Cong, Natalie May and Simon Carley.

Are we diagnosing disease, or deciding when a probability is high enough to act? The opening Risky Business article uses myocardial infarction and pulmonary embolism to explore uncertainty, treatment harms and why stopping investigation is different from proving that disease is absent.

Why can a cheap, straightforward treatment struggle for attention alongside more dramatic interventions? Reflecting on tranexamic acid after CRASH-2 in 2012, Simon Carley questions the appeal of expensive or technically demanding therapies and asks how clinicians can close the gap between evidence and routine practice.