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Tranexamic acid needs a make over

3 min read
Tranexamic acid needs a makeover

Why can a cheap, straightforward treatment struggle for attention alongside more dramatic interventions? Reflecting on tranexamic acid after CRASH-2 in 2012, Simon Carley questions the appeal of expensive or technically demanding therapies and asks how clinicians can close the gap between evidence and routine practice.

Ondansetron in vomiting children

6 min read

Does ondansetron help children with gastroenteritis tolerate oral rehydration, and how should concerns about cardiac rhythm be interpreted? This 2012 appraisal examines the evidence behind an FDA warning, questioning how studies in anaesthetic settings apply to emergency care and weighing potential benefit against uncertainty about harm.

Rabies management in the ED

1 min read

A bite sustained abroad can raise questions that extend beyond wound care. This short 2012 introduction to a rabies review discusses specialist advice, access to vaccination and immunoglobulin, and why relevant exposure is not limited to overseas dog bites.

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