JC: The REST trial. St Emlyn’s
Some years ago I remember speaking to a rather well known intensivist who was advocating for the extracorporeal removal of CO2 in ICU patients. His logic was that in patients …
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JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial. St Emlyn’s
I remember back at the beginning of the pandemic when we were seeing lots of patients arriving in the ED in extremis. The now familiar picture of the deeply hypoxic …
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Oxygen targets in critical care: The HOT-ICU trial. St Emlyn’s
Oxygen targets in critically ill/injured patients has been something we’ve talked about on the blog before. In general the evidence to date has suggested that the routine prescription of oxygen …
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The ‘Roid’ to Recovery? REMAP-CAP @ St Emlyn’s
This week JAMA published three important trials on the use of steroids in patients with severe COVID-19, with an additional cherry on top; a subsequent inclusive meta-analysis (totalling 7 RCTs …
Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s
We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A …
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The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s
We’ve talked about the RECOVERY trial on the blog and podcast before. This is a UK based platform trial (more on this later) looking at patients admitted to hospital with …
The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s Read More »