JC: The REST trial. St Emlyn’s
Some years ago I remember speaking to a rather well known intensivist who was advocating for the extracorporeal removal of CO2 in ICU patients. His logic was that in patients …
Some years ago I remember speaking to a rather well known intensivist who was advocating for the extracorporeal removal of CO2 in ICU patients. His logic was that in patients …
I remember back at the beginning of the pandemic when we were seeing lots of patients arriving in the ED in extremis. The now familiar picture of the deeply hypoxic …
JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial. St Emlyn’s Read More »
Oxygen targets in critically ill/injured patients has been something we’ve talked about on the blog before. In general the evidence to date has suggested that the routine prescription of oxygen …
Oxygen targets in critical care: The HOT-ICU trial. St Emlyn’s Read More »
This week JAMA published three important trials on the use of steroids in patients with severe COVID-19, with an additional cherry on top; a subsequent inclusive meta-analysis (totalling 7 RCTs …
We have previously covered the RECOVERY trial on St Emlyn’s noting that the first results out of this large pragmatic, adaptive design platform RCT showed no benefit to Hydroxychloroquine. A …
Dexamethasone, COVID-19 and the RECOVERY trial. St Emlyn’s Read More »
We’ve talked about the RECOVERY trial on the blog and podcast before. This is a UK based platform trial (more on this later) looking at patients admitted to hospital with …
The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s Read More »