prognosis

JC: Do you see the light? Serum neurofilament light chain for prognostication following OOHCA

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Could serum neurofilament light chain help predict neurological outcomes after out-of-hospital cardiac arrest? Dan Horner’s 2019 appraisal examines an analysis of TTM trial samples, considering promising test performance alongside validation gaps, false predictions and the risks of relying on a biomarker in isolation.

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JC: Do early pupil responses predict outcome in cardiac arrest? St Emlyn’s

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What can early pupil responses tell us after cardiac arrest? This 2018 review examines a large French observational study, separating association with outcome from the ability to predict an individual patient’s recovery. It challenges decisions based on a single early finding and considers how prognosis is discussed.

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