Could the ADAPT protocol identify chest-pain patients suitable for earlier discharge? This 2012 appraisal examines its combination of risk scoring and serial troponin testing, then questions symptom timing, external validation, assay choice and how many patients might actually avoid further investigation.
Low risk chest pain? ADAPT my management? Read More
Did the 6S trial change the case for starch-based resuscitation fluids? This 2012 journal club reviews hydroxyethyl starch versus Ringer’s acetate in severe sepsis, examining randomisation, blinding and the mortality findings, and asking how the results should influence interpretation of the crystalloid–colloid debate.
JC: The end for potatoes on the ICU…? Read More
How should the early risks of stroke thrombolysis be weighed against later functional outcomes? This 2012 journal club debates IST-3, contrasting early mortality and bleeding with six-month survival and independence, and examining how the trial’s results are presented and interpreted.
JC: Thrombolysis in Acute Stroke – IST3 Read More
