#Trauma

JC: CRYOSTAT-2 with Ross Davenport

This 2018 introduction explains the question behind CRYOSTAT-2: could early cryoprecipitate improve survival after major traumatic bleeding? It outlines the rationale for fibrinogen replacement, the planned randomised trial, eligibility criteria and patient-centred outcomes. This is a preview of the study, before its results became available.

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JC : Paracetamol, NSAID’s or both in MSK trauma. St.Emlyn’s

Is paracetamol alone enough for pain after minor musculoskeletal injury? This 2017 review examines a randomised non-inferiority trial comparing paracetamol, diclofenac and their combination. It explores pain outcomes, trial design and exclusions, including why the findings cannot simply be extended to fractures or all painful injuries.

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