overdose

Management of paracetamol therapeutic excess in the ED. St.Emlyn’s.

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How does repeated excess paracetamol taken for pain differ from other overdose presentations? This 2017 discussion explores therapeutic excess, risk assessment and the consequences for admission. It repeatedly stresses checking current TOXBASE or local toxicology guidance, rather than relying on the historical thresholds described in the post.

Management of paracetamol therapeutic excess in the ED. St.Emlyn’s. Read More

JC: Should we halve the time of acetylcysteine infusions for Paracetamol OD? St.Emlyn’s

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Could a shorter acetylcysteine infusion make treatment for paracetamol poisoning easier to tolerate? This 2014 journal club examines a randomised trial of an accelerated regimen, separating findings about nausea and infusion reactions from the larger question of effectiveness in preventing serious liver injury.

JC: Should we halve the time of acetylcysteine infusions for Paracetamol OD? St.Emlyn’s Read More

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