JC: ISARIC. Possibly The Best COVID-19 Risk Prediction Tool To Date

Has your department been relying on clinical gestalt to risk stratify patients, perhaps using something you heard or read about in a short paper (perhaps Twitter), maybe something like post-exertional oxygenation has caught your eye,

JC: TXA in severe head injury. St Emlyn’s

Our post on the CRASH-3 trial, an RCT examining the use of TXA in head injury, was arguably our most controversial of 2019 (1). Our view was that the evidence was not entirely definitive, but

August Round Up – Podcast

Welcome to our audio round up of everything on the blog during August. As the world continues to be in the grips of the Coronavirus pandemic there have been more papers looking at all aspects

The ‘Roid’ to Recovery? REMAP-CAP @ St Emlyn’s

This week JAMA published three important trials on the use of steroids in patients with severe COVID-19, with an additional cherry on top; a subsequent inclusive meta-analysis (totalling 7 RCTs and 1703 patients) from the

GBL Overdose and what to do about it

In what seems like an age ago I was asked to speak about Chemsex  at the EuSEM conference in Prague. It was a (somewhat scary) privilege to talk to the crowd about Chemsex and in

JC: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock. The ACTS Randomized Clinical Trial St Emlyn’s

Back in 2017 the sepsis world had a rather strong reaction to a paper published by Paul Marik that suggested that a combination of steroid, vitamin C and Thiamine could cure sepsis. The data, published

Covid-19 Journal Club: The Director’s Cut #6

The Emergency Medicine Academic Group based out of Leicester have given us another fantastic directors cut. Check out their work here! Professor Tim Coates and Dr Mohammed Elwan have searched every COVID-19 publication, and summarised

Look at what they make you give

Ed – We received this post just as the extent of the Coronavirus pandemic was becoming clear and thought it best to delay publishing until life in our Emergency Departments was slightly more “normal”. The

JC: Does post exposure prophylaxis (with HCQ) work in Covid-19?

The utility of hydroxychloroquine in the management of Covid-19 often seems to be more of a political than a medical debate. Many politicians, journalists, hacks, and a whole range of social media experts have an

CODA ZERO is here. St Emlyn’s

This week marks the return of CODA, or rather the start of the CODA project that developed from the genre changing SMACC conferences. I was lucky enough to be involved in setting up the first


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